This work is licensed under a Table 3.
Echocardiographic findings at diagnosis (initial) and most recent echocardiogram (latest) following treatment for lupus myocarditis.
| Initial echocardiogram in lupus myocarditis group | Latest echocardiogram in lupus myocarditis group | ||
|---|---|---|---|
| Total n = 19 | Median (IQR)/ratio (%) of test done | Median (IQR)/ratio (%) of test done | P value |
| Structural parameter | |||
| LAa diameter (cm) | 3.3 (2.8–3.9) | 3 (2.5–3.4) | 0.088 |
| LVIDb (cm) | 5.3 (4.5–5.6) | 4.8 (4.0–5.6) | 0.106 |
| RVIDc (cm) | 3.1 (3.0–3.9) | 3 (2.6–3.2) | 0.071 |
| Valvular dysfunction (mild/moderate) | 10/19 (52.6) MR | 5/19 (26.3) MR | |
| 5/17 (29.4) TR | 5/17 (29.4) TR | ||
| Pericardial effusion | 6/18 (33.3) small | Small 2/18 (11.1) | |
| 1/18 (5.6) large | |||
| Regional function parameter | |||
| RWMA present | 17/17 (100) | 16/17 (94.1) | |
| Wall motion scored | 1.88 (1.69–2.38) | 1.50 (1.31–2.00) | 0.017 |
| Global function parameter | |||
| MA E′avee (cm/s) | 8.0 (6.0–11.0) | 8.8 (5.8–10.0) | 0.649 |
| MA E/E′f | 11.6 (10.0–16.2) | 10 (7.75–15.8) | 0.281 |
| LVEFg: numerical (%) | 35 (32–46) | 47 (37–50) | 0.023 |
| LVEF: categorical | |||
| ≥55% | 0/19 (0) | 3/19 (15.8) | |
| 45–54% | 5/19 (26.3) | 10/19 (52.6) | |
| 36–44% | 4/19 (21.1) | 2/19 (10.5) | |
| ≤35% | 10/19 (52.6) | 4/19 (21.1) | |
| TAPSEh (cm) | 1.9 (1.6–2.1) | 1.7 (1.6–2.0) | 0.395 |
| Impaired GLSi | 13/13 (100) | 13/13 (100) | |
| GLS(%) | −13.0 (−13.5 to −10.3) | −15 (−14 to −5) | 0.47 |
LA diameter: normal ≤3.8 cm; bLVID: normal ≤5.3 cm; cRVID: normal ≤4.2 cm; dWall motion score increased if >1; eMA E′ average: normal <8 cm/s; fMA E/E′: normal <8; increased LV filling pressure >15; gLVEF: normal ≥55%; mild impairment: 45–54%; moderate impairment: 36–44%; severe impairment: ≤35%; hTAPSE: normal ≥1.6 cm; iGLS: normal −19.7% (95% CI, −20.4 to −18.9%).
E′ave, early diastolic mitral annular velocity, average of lateral and septal measurement; E/E′, ratio of mitral peak velocity of early filling (E) to early diastolic mitral annular velocity (E′); GLS, global longitudinal strain; IQR, interquartile range; LA, left atrium; LVEF, left ventricular ejection fraction; LVID, left ventricular internal diameter; MA, mitral annular; MR, mitral regurgitation; RVID, right ventricular internal diameter; RWMA, regional wall motion abnormalities; TAPSE, tricuspid annular plane systolic excursion; TR, tricuspid regurgitation.