Table III.
Influence of antihypertensive treatment on blood pressure and PWV
| Parameter | Visit | Quinapril (N = 19) | Amlodipine (N = 19) | HCTZ (N = 19) | Losartan (N = 19) | Bisoprolol (N = 19) | All (N = 19) | PANOVA(1;2;3) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | ||||||||
| SBP [mm Hg] | 1 | 157.5 (21.5) | 157.9 (19.2) | 152.7 (19.2) | 150.4 (17.8) | 147.0 (16.7) | 153.2 (19.0) | 0.16 | 0.000 | 0.90 |
| 2 | 149.9 (19.9) | 144.9 (19.2) | 139.4 (12.8) | 145.1 (22.1) | 139.4 (13.0) | 143.5 (17.6) | ||||
| 3 | 148.4 (17.7) | 142.3 (15.1) | 137.5 (14.5) | 140.2 (23.4) | 135.9 (14.8) | 140.7 (17.2) | ||||
| 4 | 141.6 (21.9) | 139.9 (16.2) | 134.6 (10.9) | 137.7 (12.6) | 131.5 (13.0) | 136.9 (15.4) | ||||
| DBP [mm Hg] | 1 | 91.7 (9.4) | 97.1 (9.1) | 98.2 (10.0) | 93.9 (8.8) | 91.1 (10.4) | 94.5 (9.8) | 0.09 | 0.000 | 0.87 |
| 2 | 88.0 (11.9) | 88.8 (11.9) | 89.6 (8.2) | 88.5 (9.9) | 85.6 (6.7) | 88.0 (9.7) | ||||
| 3 | 87.1 (8.1) | 88.2 (8.6) | 90.3 (8.5) | 85.7 (5.3) | 84.1 (8.7) | 87.3 (8.3) | ||||
| 4 | 83.7 (12.2) | 87.5 (10.4) | 88.1 (8.2) | 84.5 (6.5) | 80.4 (7.6) | 85.1 (9.3) | ||||
| PWV [m/s] | 1 | 10.5 (1.9) | 10.1 (1.3) | 10.8 (1.7) | 10.8 (1.6) | 10.5 (1.5) | 10.5 (1.6) | 0.87 | 0.005 | 0.66 |
| 2 | 10.7 (1.9) | 9.8 (1.2) | 10.2 (1.4) | 10.5 (1.4) | 10.1 (1.9) | 10.1 (1.6) | ||||
| 3 | 10.2 (1.8) | 10.0 (1.8) | 10.4 (1.2) | 10.6 (1.5) | 10.0 (1.9) | 10.2 (1.7) | ||||
| 4 | 9.7 (1.9) | 9.9 (1.6) | 10.3 (1.2) | 10.3 (1.5) | 10.1 (1.9) | 10.0 (1.7) | ||||
Data are given as mean (SD); PANOVA 1,2,3 : P1, main effect between group difference; P2, for variable change in time, P3, for interaction (group/variable); HCTZ – hydrochlorothiazide, SBP – office systolic blood pressure, DBP – office diastolic blood pressure, PWV – carotid femoral pulse wave velocity.