Figure 2.

Measurement of reactive oxygen species formation. Reactive oxygen species were measured in aortic tissue of MRP1^–/– LDLr^–/– double knockout mice and LDLr^–/– single knockout controls using L-012 enhanced chemiluminescence. The amount of ROS in MRP1^–/– LDLr^–/– double knockout mice was significantly lower than in LDLr^–/– controls

Data are presented as mean ± standard error of the mean; n = 5–6; *p < 0.05. LDLr – low-density lipoprotein receptor, MRP1 – multidrug resistance-associated protein 1, RLU – relative light units.