Table III.
Correlations coefficients between FGF-23, iron and inflammatory parameters in patients with CKD
| iFGF-23[pg/ml] | hsCRP [mg/l] | Hepcidin [ng/ml] | sTfR [nmol/l] | Iron [µg/dl] | Ferritin [ng/ml] | Fibri-nogen [mg/dl] | eGFR [ml/min/1.73 m2] | IL-6 [pg/ml] | |
|---|---|---|---|---|---|---|---|---|---|
| iFGF-23 [pg/ml] | x | –0.02 | –0.05 | 0.1 | 0.09 | –0.04 | –0.23* | –0.36* | 0.2 |
| hsCRP [mg/l] | x | 0.26* | 0.06 | –0.42* | 0.29* | 0.69* | –0.16 | 0.45* | |
| Hepcidin [ng/ml] | x | 0.36* | 0.19 | 0.68* | 0.21 | –0.13 | 0.28* | ||
| sTfR[nmol/l] | x | –0.36* | –0.37* | 0.04 | –0.08 | 0.12 | |||
| Iron [µg/dl] | x | 0.27* | –0.36* | 0.07 | –0.28* | ||||
| Ferritin[ng/ml] | x | 0.13 | –0.01 | 0.15 | |||||
| Fibrinogen [mg/dl] | x | –0.04 | 0.23* | ||||||
| eGFR [ml/min/1.73m2] | x | –0.35* | |||||||
| IL-6 [pg/ml] | x |
eGFR – estimated glomerular filtration rate, FGF-23 – fibroblast growth factor 23, hsCRP – high-sensitivity C-reactive protein, IL-6 – interleukin 6, sTfR – soluble transferrin receptor, WBC – white blood count. *Statistically significant data (p < 0.05).