Table IV.
Correlations between initial insulin resistance/sensitivity indices and 3-month changes in obesity parameters
| Parameter | Group M | Group O | |||||
|---|---|---|---|---|---|---|---|
| Log 120-insulin* | Log ISI | Log HOMA-IR | Log 120-insulin | Log ISI | Log HOMA-IR | ||
| Anthropometry: | |||||||
| BMI [kg/m2] | NS | NS | NS | NS | NS | NS | |
| Waist [cm] | –0.40 | 0.38 | –0.30 | –0.51 | 0.40 | NS | |
| DXA measurements: | |||||||
| Fat (%) | –0.37 | 0.56 | NS | –0.33 | 0.40 | NS | |
| Fat [kg] | –0.38 | 0.42 | NS | –0.29 | 0.39 | NS | |
| Android fat [kg] | –0.38 | 0.31 | –0.40 | NS | 0.30 | NS | |
| Gynoid fat [kg] | –0.31 | NS | NS | NS | NS | NS | |
| Android/gynoid fat | –0.40 | 0.35 | –0.42 | NS | NS | NS | |
| Trunk fat [kg] | –0.40 | 0.47 | –0.30 | –0.30 | 0.31 | –0.34 | |
| Trunk/total fat | –0.36 | 0.40 | NS | –0.29 | 0.33 | NS | |
*As measured by oral glucose tolerance test. ISI Matsuda and HOMA-IR indices in all groups. M – metformin and diet group, O – orlistat and diet group, BMI – body mass index, HOMA-IR – homeostatic model assessment-insulin resistance, ISI – insulin sensitivity index.