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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Quant Biol. 2017 Mar 30;5(1):3–24. doi: 10.1007/s40484-017-0093-6

Figure 2. Quality screening with SEQualyzer.

Figure 2

Bars represent per-nucleotide SNR and black lines represent rolling mean of per-nucleotide SNR for windows of 20 nt. SEQualyzer estimates SNR via bootstrap as described by Choudhary et al. [59]. Examination of quality profiles reveals that signal quality is good for entire RNA except a short region from nucleotides 35–53 where it is poor in all replicates. For illustration purpose, we used data for P4 – P6 domain of Tetrahymena group I intron ribozyme from Loughrey et al. [33].