Skip to main content
. Author manuscript; available in PMC: 2017 Jul 14.
Published in final edited form as: Aliment Pharmacol Ther. 2014 May 11;40(1):93–104. doi: 10.1111/apt.12788

Table 2.

Comparison of baseline predictors of response with patients that achieved a complete virological response or a virological response.

Complete Virological Response^ Virological Response°
Yes No p-value Yes No p-value
N 3 8 5 6
Age (years)* 49±4 41±14 0.311 45±15 42±12 0.271
ALT (U/L)* 98±93 181±155 0.311 84±70 221±161 0.071
Alkaline Phosphatase (U/L)* 62±10 123±60 0.0661 78±29 129±68 0.21
Bilirubin (mg/dL)* 0.6±0.2 1±0.4 0.0641 0.6±0.2 1.1±0.3 0.0061
HBV-DNA >1000 IU/mL (%) 1 (33%) 1 (13%) 0.492 1 (20%) 1 (17%) 1.02
HBsAg (log10 IU/mL)* 3.4±0.6 3.8±0.6 0.311 3.2±0.6 4.0±0.3 0.051
HDV RNA (log10 GE/mL)* 6.2±1.2 6.9±1.2 0.411 6.1±1.3 7.3±0.9 0.201
HAI Inflammation (median) 12 (7–14) 10 (7–14) 0.921 12 (7–14) 10 (7–14) 0.781
Fibrosis (median, range) 3 (3–3) 4 (3–6) 0.091 3 (3–4) 4 (3–6) 0.111
Platelets (1000/uL)* 153±71 138±54 0.841 142±56 143±60 1.01
HVPG (mmHg)* 8±0 11±7 0.791 12±89 9±4 0.521
rs12979860 genotype (n=10) 1.02 1.02
 CC 1 (50%) 4 (50%) 2 (50%) 3 (50%)
 CT 1 (50%) 4 (50% 2 (50%) 3 (50%)
1

Mann-Whitney test

2

Fisher’s exact test

*

Mean (range)

^

Complete Virological Response = Undetectable HDV RNA in serum and seroconversion of HBsAg

°

Virological Response = Undetectable HDV RNA in serum