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. Author manuscript; available in PMC: 2017 Nov 16.
Published in final edited form as: ACS Chem Neurosci. 2016 Sep 20;7(11):1543–1551. doi: 10.1021/acschemneuro.6b00186

Figure 5. Time course of behavioral changes after s.c. of L-DOPA, alone or in combination with ML218.

Figure 5

The data shown are mean values (± SEM) of the number of movements (A) and activity counts (B) obtained for each observation period starting 15 min after L-DOPA injection (values are corrected to the pre-injection baseline and normalized to the number of minutes per observation period). ML218 (or the vehicle Tween 80) were administered 60 min before L-DOPA administration. The two experimental conditions were compared at each time point (Mann-Whitney test), no significant differences were found.