TABLE 2.
Comparison of Normal OGTT to Prediabetic OGTT Group
| Normal OGTT (n = 170) | Prediabetes OGTT (n = 60) | P | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age (years) | 13.33 | 2.90 | 14.07 | 2.80 | 0.0889 |
| BMI z score | 2.33 | 0.41 | 2.22 | 0.38 | 0.055 |
| A1C (%) | 5.64 | 0.47 | 5.89 | 0.46 | 0.0005 |
| LDL cholesterol (mg/dL) | 95.41 | 27.78 | 87.32 | 26.22 | 0.65 |
| Median | 25th–75th Percentile | Median | 25th–75th Percentile | P | |
|---|---|---|---|---|---|
| AUC glucose | 104.25 | 95.5–111.7 | 130.38 | 114.9–155 | <0.0001 |
| AUC insulin | 99.59 | 68.0–144.8 | 117.93 | 73.3–198.9 | 0.0956 |
| HOMA-IR | 4.60 | 3.17–6.79 | 5.66 | 4.02–10.52 | 0.013 |
| Insulin (mU/L) | |||||
| Fasting | 21.8 | 14.76–32.0 | 25.90 | 16.7–39.3 | 0.10 |
| 1-h | 129.85 | 77.7–195.6 | 138.0 | 75.5–261.7 | 0.45 |
| 2-h | 106.90 | 66.8–197.9 | 176.90 | 97.95–257.60 | 0.016 |
| Glucose (mg/dL) | |||||
| Fasting | 89.0 | 83.0–92.0 | 100 | 93.5–106.5 | <0.001 |
| 1-h | 115.0 | 97.0–135.0 | 146.0 | 119.0–175.0 | <0.001 |
| 2-h | 102.0 | 93.0–113.0 | 140.5 | 119.5–157.0 | <0.001 |
| Total cholesterol (mg/dL) | 156.0 | 139–180.0 | 148.5 | 130.0–175.0 | 0.17 |
| Triglycerides (mg/dL) | 79.0 | 58.0–103.0 | 83.0 | 55.0–115.0 | 0.55 |
| HDL cholesterol (mg/dL) | 43.55 | 36.0–50.2 | 42.10 | 36.6–47.2 | 0.60 |
To convert to SI units: A1C (mmol/mol) = 10.93 × A1C (%) – 23.5; glucose (mmol/L) = glucose (mg/dL) × 0.0555; insulin (pmol/L) = insulin (mU/L) × 6.945; cholesterol (mmol/L) = cholesterol (mg/dL) × 0.0259; triglyceride (mmol/L) = triglyceride (mg/dL) × 0.0113; HDL (mmol/L) = HDL (mg/dL) × 0.0259; LDL (mmol/L) = LDL (mg/dL) × 0.0259. Boldface P values indicate statistical significance.