Table 2.

Central composite design matrix and corresponding responses

Run	Variables			Responses
	A	B	C	R1 (EEQ)	R2 (EEP)
1	15.00	8.00	5.00	51.69	74.25
2	15.00	5.00	5.00	81.17	86.43
3	15.00	5.00	5.00	83.21	83.51
4	15.00	5.00	2.00	87.74	91.4
5	12.00	3.20	3.20	98.12	92.62
6	10.00	5.00	5.00	76.25	82.02
7	12.00	3.20	6.80	79.59	84.44
8	18.00	3.20	3.20	89.92	84.78
9	18.00	3.20	6.80	75.25	77.32
10	12.00	6.80	6.80	66.38	76.39
11	12.00	6.80	3.20	70.24	87.14
12	20.00	5.00	5.00	61.05	73.53
13	15.00	2.00	5.00	91.68	85.26
14	18.00	6.80	3.20	53.92	80.83
15	15.00	5.00	5.00	82.36	85.89
16	15.00	5.00	5.00	80.69	85.87
17	15.00	5.00	5.00	81.67	85.45
18	15.00	5.00	5.00	82.88	82.25
19	18.00	6.80	6.80	54.18	68.54
20	15.00	5.00	8.00	71.08	72.86

Abbreviations: EEQ, encapsulation efficiency of coenzyme Q10; EEP, encapsulation efficiency of D-panthenyl triacetate.