. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Dev Psychopathol. 2016 Jul 18;29(3):901–917. doi: 10.1017/S0954579416000560

Table 2.

The interaction of prenatal maternal depression and child 5-HTTLPR, DRD4 and a multilocus genetic profile score in the prediction of Negative Emotionality from 3 to 36 months (mixed models)

Predictors	5-HTTLPR	DRD4	Multilocus Genetic Profile Score
Prenatal depression	0.001	−0.000	−0.003
Genotype	0.139^*	−0.004	0.049
Prenatal depression X genotype(s)(interaction)	0.016^*	0.015^*	0.013^**
Covariates
Postnatal depression	0.016^***	0.018^***	0.018^***
Maternal education – College	0.197^*	0.179^*	0.186^*
Maternal education – University	0.150^t	0.165^*	0.157^*
Gender	0.009	0.016	0.022
Mother age of birth	−0.015	−0.015^*	−0.017^*
Site	0.038	0.057	0.051
Maternal 5-HTTLPR	−0.137^*	-	−0.102

Note. Multilocus genetic profile score − 0, 1 or 2 risk/susceptibility genotype (no L_A (S/S, S/L_G or L_G/L_G)(5-HTTLPR); 6–8R (DRD4)). In the model with 5-HTTLPR McFadden’s pseudo R² = .065, χ²(9) = 112.16*** (AIC: 920.8) -, in the model with DRD4 McFadden’s pseudo R² = .059, χ²(9) = 112.49***, in the model with the multilocus genetic profile score McFadden’s pseudo R² = .066, χ²(9) = 112.04*** (AIC – 922).

p < .10

p < .05

^**

p < .01

^***

p < .001