Table 3.
Candidate selection comparing cases with controls in the discovery phase
| Protein | IPA1: De novo chronic GVHD | IPA2: Quiescent chronic GVHD | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MS Ratio | ELISA Ratio | Ratio Consistency | AUC | Candidate | MS Ratio | ELISA Ratio | Ratio Consistency | AUC | Candidate | |
| IGHM | 4.5 | 1.3 | Yes | 0.58 | No | 6.31 | 1.4 | Yes | 0.51 | No |
| HPR | 2.4 | 0.65 | No | – | No | 2.59 | 0.86 | No | – | No |
| LGALS3BP | 1.9 | 1.43 | Yes | 0.68 | Yes | 2.45 | 1.59 | Yes | 0.64 | Yes |
| GIP | 2.1 | 1.00 | No | – | No | 2.11 | 0.63 | No | – | No |
| CD5L | 2.2 | 1.83 | Yes | 0.66 | Yes | 2.1 | 1.63 | Yes | 0.66 | Yes |
| LTBP2 | 1.6 | 0.85 | No | – | No | 1.63 | 0.93 | No | – | No |
| CD163 | 1.7 | 1.34 | Yes | 0.73 | Yes | |||||
| CRTAC1 | 1.6 | NA | No | – | No | |||||
| TFF2 | 1.7 | 0.94 | No | – | No | |||||
| TXN | 1.7 | 2.13 | Yes | 0.70 | Yes | |||||
| HSP90B1 | 0.6 | 2 | No | – | No | |||||
| PDLIM1 | 0.6 | 3.11 | No | – | No | |||||