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Representative anatomy images demonstrate reduced EBD uptake and fibrosis after FTY720 treatment. The FTY720-treated diaphragm (B) contained less EBD and fewer fibrotic fibers than the control diaphragm (A). The control heart (C) displayed extensive fibrosis throughout the right ventricle (delineated by arrows, and focused upon in the inset). The treated heart (D) had smaller regions of fibrosis (indicated by an arrow) at the edges of the right ventricle. Black bars: 3 mm.
