Table 1.
EBD | Abdominals | Quadriceps | Gas/Sol | Hamstrings | Triceps |
---|---|---|---|---|---|
WT+DMSO | |||||
Average | 63.87 | 11.80 | 22.14 | 26.79 | 19.53 |
Standard error | 7.69 | 4.46 | 3.18 | 3.02 | 4.72 |
N | 5 | 5 | 5 | 5 | 5 |
WT+FTY720 | |||||
Average | 48.78 | 9.41 | 10.69 | 18.98 | 11.54 |
SE | 7.73 | 5.59 | 2.63 | 4.87 | 1.60 |
N | 5 | 5 | 5 | 5 | 5 |
Sgcg+DMSO | |||||
Average | 65.31 | 59.50 | 41.05 | 52.65 | 66.30 |
Standard error | 8.16 | 6.97 | 5.55 | 4.53 | 8.71 |
N | 8 | 8 | 8 | 8 | 8 |
Sgcg+FTY720 | |||||
Average | 38.81 | 26.77 | 20.20 | 30.31 | 24.47 |
Standard error | 5.77 | 6.33 | 3.81 | 5.66 | 3.78 |
N | 13 | 12 | 13 | 13 | 13 |
ANOVA P-value | 0.001 | 0.001 | 0.005 | 0.022 | 0 |
| |||||
EBD normalized to kidney values | Abdominals | Quadriceps | Gas/Sol | Hamstrings | Triceps |
| |||||
WT+DMSO | |||||
Average | 0.5516 | 0.0931 | 0.1870 | 0.2248 | 0.1632 |
Standard error | 0.0878 | 0.0400 | 0.0182 | 0.0215 | 0.0424 |
N | 5 | 5 | 5 | 5 | 5 |
WT+FTY720 | |||||
Average | 0.6130 | 0.1190 | 0.1317 | 0.2342 | 0.1407 |
Standard error | 0.1324 | 0.0784 | 0.0381 | 0.0655 | 0.0209 |
N | 5 | 5 | 5 | 5 | 5 |
Sgcg+DMSO | |||||
Average | 0.7366 | 0.5019 | 0.3973 | 0.5039 | 0.6016 |
Standard error | 0.0882 | 0.0472 | 0.0637 | 0.0669 | 0.0626 |
N | 8 | 8 | 8 | 8 | 8 |
Sgcg+FTY720 | |||||
Average | 0.5726 | 0.4352 | 0.2957 | 0.4270 | 0.3638 |
Standard error | 0.0305 | 0.0446 | 0.0255 | 0.0332 | 0.0304 |
N | 13 | 12 | 13 | 13 | 13 |
ANOVA P-value | 0.363 | 0 | 0.009 | 0.008 | 0 |
| |||||
HOP | Abdominals | Diaphragm | Heart | Quadriceps | Hamstrings |
| |||||
WT+DMSO | |||||
Average | 9.90 | 7.91 | 2.29 | 2.67 | 2.72 |
Standard error | 2.32 | 1.93 | 1.36 | 2.88 | 1.15 |
N | 5 | 5 | 5 | 5 | |
WT+FTY720 | 5 | ||||
Average | 5.90 | 15.85 | 3.49 | 3.84 | 3.23 |
Standard error | 1.22 | 4.98 | 2.24 | 1.18 | 0.53 |
N | 6 | 6 | 6 | 6 | 6 |
Sgcg+DMSO | |||||
Average | 23.48 | 18.11 | 5.46 | 21.31 | 14.36 |
Standard error | 6.32 | 4.46 | 1.14 | 5.11 | 3.94 |
N | 9 | 9 | 9 | 9 | 9 |
Sgcg+FTY720 | |||||
Average | 10.57 | 7.97 | 2.76 | 13.82 | 7.41 |
Standard error | 0.81 | 0.84 | 0.40 | 1.80 | 0.52 |
N | 14 | 14 | 14 | 14 | 14 |
ANOVA P-value | 0.006 | 0.04 | 0.019 | 0.006 | 0.013 |
Gas, gastrocnemius; Sol, soleus; WT, wild-type. See text for other abbreviations.