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. 2017 Jul 14;7:5480. doi: 10.1038/s41598-017-05726-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pan-cancer overview of the top 20 signatures by several metrics (from top to bottom): normalized enrichment score, tag (sensitivity), list (false-negative rate), signal (enrichment strength) and the mean ranks of the previous metrics. Histograms are sorted to display best to worst ranks from top to bottom, respectively. CINSARC signatures are highlighted in black.