. 2017 Mar 13;36(28):3943–3956. doi: 10.1038/onc.2016.502

Table 2. Genes reported as being directly repressed by p53, and contradictory findings.

Gene	Reports of direct repression	Reported contradictions
ABCB1 (MDR1)	⁸²	Activated, not repressed²⁶¹
		Not bound or regulated by p53⁵³
ANLN	²⁶²	Repression requires p107/p130²⁶³
BCL2	^{190, 191}	Not bound or regulated by p53⁵³
BIRC5 (Survivin)	^{264, 265, 266, 267}	Not bound by p53^{92, 107, 268}
		Repression requires p21^{92, 93, 107}
		Repression requires p107/p130²⁶³
BNIP3	²⁶⁹	Not bound or regulated by p53⁵³
CCNB1	^{270, 271}	Not bound by p53^{53, 108}
		Repression requires p21^{53, 92, 94, 100, 108}
		Repression requires p107/p130²⁶³
CCNB2	⁸⁶	Repression requires p21^{95, 101, 109}
		Repression requires p107/p130²⁶³
CD44	⁸³	Not bound by p53⁵³
		Not regulated by p53^{53, 272}
CDC20	²⁷³	Not bound by p53⁵³
		Repression requires p21^{93, 96}
		Repression requires p107/p130²⁶³
CDC25B	²⁷⁴	Repression requires p21⁹⁵
CDC25C	^{275, 276}	Not bound by p53¹⁰⁷
		Repression requires p21^{92, 107}
		Repression requires p107/p130²⁶³
CDK1 (CDC2)	^{86, 276}	Not bound by p53⁵³
		Repression requires p21^{53, 90, 92, 94, 98, 100, 101}
		Repression requires p107/p130²⁶³
CKS2	²⁷⁷	Repression requires p107/p130²⁶³
CRYZ	^{262, 278}	Not bound or regulated by p53⁵³
ECT2	²⁷⁹	Repression requires p107/p130²⁶³
HSPA8	^{262, 278}	Not bound or regulated by p53⁵³
ID2	²⁸⁰	Not bound or regulated by p53⁵³
LASP1	²⁸¹	Not bound or regulated by p53⁵³
MAD1L1	^{278, 282}	Not bound by p53⁵³
		Repression requires p21^{93, 102}
		Repression requires p107/p130²⁶³
ME1	⁸⁰	Not bound or regulated by p53⁵³
ME2	⁸⁰	Not bound or regulated by p53⁵³
ME3	⁸⁰	Not bound or regulated by p53⁵³
NEK2	²⁸³	Not bound by p53⁵³
		Repression requires p21^{53, 93}
PCNA	²⁸⁴	Activated, not repressed^{169, 285}
PLK1	^{286, 287}	Not bound by p53¹⁰⁷
		Repression requires p21^{97, 107}
		Repression requires p107/p130²⁶³
POLD1	²⁸⁸	Not bound by p53¹⁰⁸
		Repression requires p21^{92, 108}
PRC1	²⁸⁹	Repression requires p21⁹³
		Repression requires p107/p130²⁶³
PTK2 (FAK)	²⁹⁰	Not bound or regulated by p53⁵³
RAD51	¹⁷³	Repression requires p21⁹⁴
SCD	²⁶²	Repression requires p21²⁹¹
TPT1 (TCTP)	⁸⁴	Not bound or regulated by p53⁵³