Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 13;36(28):3986–4000. doi: 10.1038/onc.2017.29

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

Knockdown of CD133 and VEGF abolished the promoting effects of anti-miR-377 on cancer stemness and angiogenesis. (a) The increased expression levels of CD133 and VEGF in miR-377-knockdown ESCC cells were inhibited by the siRNAs against CD133 and VEGF, respectively. (b) The miR-377-knockdown ESCC cells transfected with si-CON or two different siRNAs against CD133 were compared for ability to form spheres over serial passages. (c) Effects of conditioned medium (CM) from ESCC cells with the indicated manipulation of miR-377 and VEGF expressions on the tube-formation activity of HUVECs. Bars, s.d.; *P<0.05; **P<0.01.