Table 2.
Potential virulence determinants identified in six S. equorum genomes.
| Virulence factor | Gene locus | |||||
|---|---|---|---|---|---|---|
| KM1031 | C2014 | KS1039 | Mu2 | UMC-CNS-924 | G8HB1 | |
| Haemolysis-related | ||||||
| Haemolysin | AWC34_RS03405 | AVJ22_RS03205 | SEQMU2_RS08595 | SEQU_RS25035 | UF72_RS01895 | |
| Haemolysin III | AWC34_RS09060 | AVJ22_RS09420 | SE1039_RS09485 | SEQMU2_RS01345 | SEQU_RS26575 | UF72_RS08525 |
| Haemolysin activation protein | AWC34_RS11995 | AVJ22_RS12370 | SE1039_RS12450 | SEQMU2_RS04245 | SEQU_RS16015 | UF72_RS08300 |
| SEQU_RS16020 | ||||||
| SEQU_RS16025 | ||||||
| Haemolysin family calcium-binding region | AVJ22_RS14095* | |||||
| Antibiotic resistance | ||||||
| Efflux pump | ||||||
| Chloramphenicol resistance protein DHA1 | AWC34_RS10365 | AVJ22_RS10770 | SE1039_RS10790 | SEQMU2_RS02670 | SEQU_RS15060 | UF72_RS09825 |
| Lincomycin resistance protein LmrB | AWC34_RS12700 | AVJ22_RS13165 | SEQMU2_RS05490 | SEQU_RS20895 | UF72_RS07545 | |
| Quinolone resistance protein NorB | AWC34_RS00175 | AVJ22_RS00115 | SE1039_RS00130 | SEQMU2_RS05750 | SEQU_RS20615 | UF72_RS07265 |
| Quinolone resistance protein NorB | AWC34_RS10900 | AVJ22_RS13260 | SE1039_RS11310 | SEQMU2_RS03165 | SEQU_RS23900 | UF72_RS10355 |
| Multidrug resistance protein SepA | AWC34_RS09050 | AVJ22_RS09410 | SE1039_RS09475 | SEQMU2_RS01335 | SEQU_RS26585 | UF72_RS08515 |
| Multidrug resistance protein SMR | AWC34_RS00690 | AVJ22_RS00690 | SE1039_RS00770 | SEQMU2_RS06295 | SEQU_RS23055 | UF72_RS06755 |
| Antibiotic ABC transporter ATP-binding protein | AWC34_RS11115 | SEQU_RS24115 | UF72_RS10570 | |||
| Tetracycline resistance MFS efflux pump | SEQU_RS26615* | |||||
| Enzymatic inactivation | ||||||
| Methicillin resistance protein | AWC34_RS05640 | AVJ22_RS05905 | SE1039_RS06065 | SEQMU2_RS11115 | SEQU_RS17120 | UF72_RS04430 |
| Methicillin resistance protein | AWC34_RS05645 | AVJ22_RS05910 | SE1039_RS06070 | SEQMU2_RS11120 | SEQU_RS17125 | UF72_RS04435 |
| Methicillin resistance protein FemA | AWC34_RS11375 | AVJ22_RS11680 | SE1039_RS11790 | SEQMU2_RS03635 | SEQU_RS17305 | UF72_RS10830 |
| β-Lactamase | AWC34_RS13020* | AVJ22_RS12330 | SEQMU2_RS04220 | SEQU_RS22365 | UF72_RS12370 | |
| Lincomycin resistance protein LnuA | AWC34_RS13300* | SEQU_RS26665* | ||||
| Other | ||||||
| Antibiotic biosynthesis monooxygenase | AWC34_RS01805 | |||||
*Genes located in a plasmid.