Table 4.
Diagnostic thresholds of eLIFT for liver fibrosis and cirrhosis.
| Cut-offs | Se,% | Sp,% | PPV,% | NPV, % | +LR | −LR | |
|---|---|---|---|---|---|---|---|
| Advanced fibrosis | 9* | 39 | 85 | 49 | 79 | 2.60 | 0.72 |
| 3** | 94 | 16 | 30 | 87 | 1.11 | 0.38 | |
| Severe fibrosis | 9* | 44 | 82 | 26 | 91 | 2.37 | 0.69 |
| 3** | 95 | 14 | 14 | 95 | 1.11 | 0.36 | |
| Cirrhosis | 10* | 42 | 88 | 25 | 94 | 3.50 | 0.65 |
| 5** | 92 | 14 | 9 | 95 | 1.07 | 0.57 |
eLIFT, the easy Liver Fibrosis Test; Se, sensitivity; Sp, specificity; PPV, positive predictive value; NPV, negative predictive value; +LR, positive likelihood ratio; −LR, negative likelihood ratio; Cut-offs* were obtained by maximizing Youden index (sensitivity + specificity−1); Cut-offs** were established by obtaining a sensitivity of at least 90%.