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. Author manuscript; available in PMC: 2017 Aug 22.
Published in final edited form as: Dev Cell. 2016 Aug 11;38(4):413–429. doi: 10.1016/j.devcel.2016.07.012

Figure 7. Knockdown of egfr-3 reduces asymmetric cell division during neoblast repopulation after sublethal irradiation.

Figure 7

(A) Immunostaining with an antibody against EGFR-3 in control(RNAi) planarians. Egfr-3 knockdown eliminates the staining. (B) Representative images showing EGFR-3 and smedwi-1 distribution in symmetric cell division. (C) Representative images showing EGFR-3 and smedwi-1 distribution in asymmetric cell division. (D) Representative images and numbers of asymmetric vs. symmetric cell divisions in control(RNAi), egfr-3(RNAi), and nrg-7(RNAi) planarians at 14 dpi. Scale bar= 10 μm. p value calculated for egfr-3(RNAi) vs. control(RNAi) and nrg-7(RNAi) vs. control(RNAi), respectively, using Two tailed Fisher's exact test. See also Figures S7.