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. Author manuscript; available in PMC: 2017 Dec 28.
Published in final edited form as: Nature. 2017 Jun 28;547(7662):173–178. doi: 10.1038/nature22969

Figure 1. Fine-mapping procedure and output using the SMAD3 region as an example.

Figure 1

a, 1) We merge overlapping signals across methods; 2) select a lead variant (black triangle) and phenotype (color); and 3) choose the best model. Details for each step are available in Methods. b, Example fine-mapping output. This region has been mapped to two independent signals. For each signal, we report the phenotype it is associated with (colored), the variants in the credible set, and their posterior probabilities.