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. Author manuscript; available in PMC: 2018 Jul 15.
Published in final edited form as: Clin Cancer Res. 2017 Feb 14;23(14):3906–3917. doi: 10.1158/1078-0432.CCR-16-2530

Figure 1.

Figure 1

MUC16 expression in lung carcinoma and association of MUC16 with lung cancer patient’s survival. A, MUC16 was observed in a smaller proportion of normal bronchial tissues (1/10) but in a higher proportion of lung carcinoma (31/101, 30.69%; P=0.03). B, MUC16 expression is associated with worse outcomes in lung cancer patients. C, MUC16 expression was retained in both primary and metastatic lymph node tissues. D, Heat map of composite score represents that MUC16 expression in both primary lung carcinoma and matched lymph node tissues. E, Immunohistochemical results show that Muc16 is strongly overexpressed in mouse lung adenocarcinoma tissues (KrasG12D; AdCre) as compared to littermate control lung tissues (KrasG12D). *P<0.05. A, C & E, Figure magnification 20X and A, lower right higher magnification 40X.