Table 4.
A U.S. cohort (n=161) – 9% HRV |
B Italian Cohort (n=101) – 17% HRV |
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EGDs avoided | HRV | Sensitivity | NPV | EGDs avoided | HRV | Sensitivity | NPV | |
Baveno criteria | 41 (26%) | 0/14 | 100% (77-100) | 100% (91-100) | 16 (16%) | 0/17 | 100% (80-100) | 100% (79-100) |
PLT >150 | 73 (45%) | 0/14 | 100% (77-100) | 100% (95-100) | 19 (19%) | 1*/17 (1%) | 94% (71-100) | 95% (75-100) |
MELD =6 | 29 (19%) | 0/14 | 100% (77-100) | 100% (88-100) | 16 (16%) | 0/17 | 100% (80-100) | 100% (79-100) |
Baveno/MELD=6 | 60 (38%) | 0/14 | 100% (77-100) | 100% (94-100) | 28 (28%) | 0/17 | 100% (80-100) | 100% (88-100) |
PLT >150/MELD=6 | 86 (54%) | 0/14 | 100% (77-100) | 100% (96-100) | 30 (30%) | 1*/17 (1%) | 94% (71-100) | 97% (83-100) |
HRV= High risk varices; EGD= esophagogastroduodenoscopy; PLT= platelet count (×1000/mm3); Baveno/MELD adds patients who do not fulfill Baveno criteria (PLT<150 and LSM >20) but have a MELD <7; PLT/MELD adds patients with a platelet count <150,000 but have a MELD =6
patient with PLT 340, LSM 22.5 and medium-sized varices