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. Author manuscript; available in PMC: 2017 Jul 16.
Published in final edited form as: Chem Commun (Camb). 2017 Feb 9;53(13):2174–2177. doi: 10.1039/c6cc09882g

Fig. 4.

Fig. 4

Structure of KDM4A in complex with Ni(II) and the lowest-energy (E)-JIB-04 conformer. (A) Surface view of KDM4A with a space-filling model of (E)-JIB-04. (B) Interactions of (E)-JIB-04 with KDM4A active site residues highlighted by dashes.