Table 3.
Comparison of PPI/H2RA users and PPI/H2RA non-users among patients with newly diagnosed celiac disease
| PPI/H2RA Users (%) | PPI/H2RA Non-Users (%) | P value | |
|---|---|---|---|
|
| |||
| Total | 22 (15) | 126 (85) | |
|
| |||
| Age (mean/median, SD) | 48.2/48.5 (16.3) | 39.0/39.5 (13.9) | 0.004 |
|
| |||
| Gender | 0.56 | ||
| Male | 8 (17) | 38 (83) | |
| Female | 14 (14) | 88 (86) | |
|
| |||
| Mode of presentation | 0.71 | ||
| Classical | 10 (16) | 52 (84) | |
| Non-classical | 12 (14) | 74 (86) | |
|
| |||
| Serologic status at time of endoscopy (TTG/DGP/EMA) | 0.002 | ||
| Seropositive | 16 (12) | 120 (88) | |
| Seronegative | 6 (55) | 5 (45) | |
|
| |||
| Distribution of villous flattening* | 1.0 | ||
| More severe in the bulb | 4 (17) | 20 (83) | |
| Less severe in the bulb | 1 (17) | 5 (83) | |
| Equal severity for bulb and D2 | 5 (15) | 29 (85) | |
*
Patients without both bulb and D2 specimens were not included.
**
Categorized by the most severe Marsh score on any given patient. Patients with unspecified histologic severity were not included.