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Incidence rates of LCNP after head and neck radiotherapy in published cohort studies are summarized by Forest Plot method. Median incidence rate of LCNP was 10.5% in long-term survivorship of NPC. While most cohorts observed incidence rates under 12%, two cohorts with long follow-up of survivors (minimum of 3.8 years) found more than 20% incidence of LCNP at median of 11.4Y follow-up. No OPC-specific incidence studies were identified in published data.
