Table 1.
Vector bio-distribution in the liver of C57BL/6 mice administered with WT-AAVrh.10 and its mutant vector 72 days post-hepatic gene transfer.
Vector type | Vector copies per mouse diploid genome (mean ± SD) |
---|---|
WT-AAVrh.10 | 0.64 ± 0.45 |
AAVrh.10-S671A | 2.07 ± 0.73 |
Values denote copy number of vectors in mouse diploid genome.