Table 2.
Comparison of baseline characteristics between age ≥ 80 and age < 80
| Characteristic | Age ≥ 80 (n = 106) | Age < 80 (n = 362) | p value |
|---|---|---|---|
| Age, yr | 83.82 ± 3.45 | 64.12 ± 12.53 | 0.000 |
| Male sex | 54 (50.9) | 252 (69.6) | 0.000 |
| Body mass index | 20.73 ± 3.71 | 21.45 ± 4.00 | 0.021 |
| SOFA score | 6.80 ± 3.98 | 8.21 ± 4.47 | 0.004 |
| APACHE II score | 17.61 ± 8.30 | 19.18 ± 8.97 | 0.109 |
| Diabetes mellitus | 25 (23.6) | 130 (35.9) | 0.018 |
| Heart disease | 26 (24.5) | 63 (17.4) | 0.100 |
| Liver disease | 5 (4.7) | 58 (16.0) | 0.003 |
| Renal disease | 18 (17.0) | 99 (27.3) | 0.030 |
| Malignancy | 8 (7.5) | 51 (14.1) | 0.074 |
| Neurovascular disease | 12 (11.3) | 45 (12.4) | 0.759 |
| Severe sepsis/septic shock | 32 (30.5) | 130 (36.4) | 0.262 |
| ARDS | 21 (19.8) | 52 (14.4) | 0.174 |
| MV (invasive) | 105 (99.1) | 345 (95.3) | 0.077 |
| Duration of MV, day | 8.33 ± 8.56 | 10.00 ± 18.78 | 0.379 |
| ICU stay, day | 8.19 ± 8.78 | 10.57 ± 19.97 | 0.079 |
| Hospital stay, day | 18.17 ± 15.45 | 27.95 ± 39.63 | 0.000 |
| Death in ICU | 37 (34.9) | 143 (39.5) | 0.392 |
| Death in hospital | 43 (40.6) | 166 (45.9) | 0.335 |
| Death, < 48 hours after ICU admission (n = 148) | 13/33 (39.4) | 62/115 (53.9) | 0.141 |
| Weaning failure | 28 (26.4) | 87 (24.0) | 0.616 |
| Unplanned extubation | 7 (6.6) | 23 (6.4) | 0.926 |
| Tracheostomy | 6 (5.7) | 44 (12.2) | 0.322 |
| Re-intubation | 8 (7.5) | 35 (9.7) | 0.506 |
| Renal replacement therapy | 20 (18.9) | 93 (25.7) | 0.149 |
| Transfusion | 29 (27.4) | 150 (41.4) | 0.009 |
| Withdrawal or withholding of intensive care in ICU | 23 (21.7) | 54 (14.9) | 0.098 |
Values are presented as mean ± SD or number (%).
SOFA, Sequential Organ Failure Assessment; APACHE II, Acute Physiology and Chronic Health Evaluation II; ARDS, acute respiratory distress syndrome; MV, mechanical ventilation; ICU, intensive care unit.