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. 2017 May-Jun;7(3):206–213.

Table1.

Therapeutic effect of Rosa damascena oil in human stadies

Author
(year)
Material Sample Method Subject research Outcomes
Hur et al., 2007 Mixed essential oils of rose ,lavender,
rose geranium
Women between 45 and 54 years of age Aroma-massage therapy Blood pressure
Lipid metabolism
↓SBP and ↓DBP in the aroma massage therapy group (SBP: p <0.05; DBP: p <0.05).
No significant differences in lipid metabolism between two groups HDL (p <0.01) and TG (p< 0.05).
Fukui et al., 2007 R. damascena oil (0.03 ml) Healthy college students Aroma therapy Endocrine system ↓Levels of cortisol in males and females. ↓Testosterone in the female subjects.
Kim et al., 2011 Mixed essential oils of Rosa centifolia,
Rosa damascena, Salvia sclarea Pelargonium graveolens, Zingiber officinale (at the concentration of 3%.)
Female nurses Aroma-massage therapy Menstrual pain ↓ Menstrual pain (p < 0.001).
↓ Level of anxiety (P = 0.001).
Farnia et al., 2015 R. damascena oil (contained 17 mg Citronellol) Male suffering from MDD and SSRI-I SD Aromatherapy Sexual dysfunction ↓Sexual dysfunction (p<0.05).
Farnia et al., 2015 R. damascena oil (contained 17 mg Citronellol) Female suffering from MDD and SSRI-I SD Aromatherapy Sexual dysfunction ↓Sexual dysfunction (p<0.05).
Ayan et al., 2013 R. damascena oil (maintained at a 2% concentration) patients with renal colic Aromatherapy Pain ↓ Pain intensity 10 and 30 minutes after treatment. (p = 0.002, p = 0.000).
Marzouk et al., 2013 Essential oils: rose, cinnamon, clove, and lavender (diluted in sweet almond oil at a final concentration of 5%) Nursing students Aromatherapy Menstrual pain ↓The level (p= 0.007) and duration (p= 0.007) of menstrual pain and the amount of menstrual bleeding.
Sadeghi et al., 2015 R. damascena oil (4% diluted in almond oil) Female nurses Aroma-massage therapy Menstrual pain ↓Pain severity (p = 0.000).
Haze et al., 2002 R. damascena oil Healthy females Aromatherapy Sympathetic activity ↓30% in adrenaline concentration (P = 0.01) and ↓ 40% in relative sympathetic activity (P= 0.01).
Igarashi et al., 2014 R. damascena oil (0.2 L) was injected to a 24-L odor bag Female university students Aromatherapy Evaluations of relaxation ↑‘‘comfortable’’, ‘‘relaxed’’ and ‘‘natural’’ feelings
↓The mean oxy-Hb concentration in the right prefrontal cortex (p<0.05).
Marofi et al., 2015 R. damascena oil Children hospitalized for surgery Aromatherapy Postoperative pain ↓Pain intensity in each time point of 3, 6, 9, and 12 h after arrival to the ward (p < 0.05).
Kheirkhah et al., 2014 R. damascena oil Nulliparous women Aromatherapy Anxiety ↓Anxiety score in transitional and active phase (p<0.001).
Hongratanaworakit, 2008 R. damascena oil
(1 ml of a 20% (w/w) solution of rose oil in sweet almond oil)
Healthy volunteers Massage therapy with rose oil Autonomic parameters and emotional responses ↓SBP, BR, BOS (p<0.03).
No significant effects on DBP and on PR (p>0.05).
↓Alertness, ↑calmness, ↑ relaxation (p=0.03 for all).
No significant effects on attentiveness, mood and vigor (p>0.05 for all).

BP: Blood Pressure, SBP: Systolic Blood Pressure, DBP: Diastolic Blood Pressure, HDL: high density Lipid, TG: Triglyceride, MDD: Major Depressive Disorder, SSRIs: Selective Serotonin-Reuptake Inhibitors, SSRI-I SD: SSRI-induced sexual dysfunction, VAS: Visual Analogue Scale, MAP: Mean Arterial Pressure, BPM: Beats Per Minute, PR: Pulse Rate, BOS: Blood Oxygen Saturation, BR: Breathing Rate, ST: Skin Temperature