Figure 1.

Effects of linalool (12.5, 25 and 50 mg/kg) on the acquisition of morphine-induced CPP in mice. During the conditioning phase animals received different treatments in the drug-paired compartment. Data are expressed as mean ± SEM of 7 animals per group. The bars represent the time spent in the drug-paired compartment before conditioning sessions in pre-conditioning test and after conditioning sessions in post-conditioning test. ^*p<0.05 and ^***p<0.001 significant differences in the time spent in the drug-paired compartment in pre-conditioning vs. post-conditioning sessions tests, NS: normal saline; Mor: Morphine