Figure 3.

Comparing the effects of different linalool doses on the reinstatement of morphine-induced conditioned place preferences. Animals received morphine 40 mg/kg for 4 consecutive days and on the 16th day, saline or different doses of linalool (12.5, 25 and 50 mg/kg) or memantine (20 mg/kg), and morphine (10 mg/kg) were injected. 3rd day, pre-conditioning phase, and 16th day, reinstatement phase. The bars represent the mean ± S.E.M. time spent in the drug paired (white) in 7 animals. ^* p<0.05 and ^** p<0.01 significant difference in the time spent in pre-conditioning sessions vs. reinstatement tests