Table 1.
Subjects, n | 741 |
Age, years | 77.5 ± 0.8 |
Body mass index | 26.3 ± 3.5 |
Systolic blood pressure, mm Hg | 151 ± 21 |
Diastolic blood pressure, mm Hg | 81 ± 10 |
Urinary albumin/creatinine ratio | 0.8 (0.3 – 2.1) |
Glomerular filtration ratea | 73 ± 17 |
Total cholesterol, mmol/L | 5.4 ± 1.0 |
HDL cholesterol, mmol/L | 1.3 ± 0.3 |
Fasting plasma glucose, mmol/L | 5.8 ± 1.2 |
C-reactive protein, mg/L | 1.8 (0.96 – 4.2) |
Interleukin 6, ng/L | 2.9 (2.1 – 4.9) |
Plasma osteopontin, ng/mL | 55 ± 26 |
Urinary osteopontin, ng/mLb | 113 ± 64 |
Lipid-lowering treatment | 125 (17) |
Antihypertensive treatment | 352 (48) |
Acetylsalicylic acid | 213 (29) |
Chronic kidney disease | 155 (21) |
Cardiovascular disease | 204 (28) |
Ischemic heart disease | 140 (19) |
Cerebrovascular disease | 73 (10) |
Congestive heart failure | 35 (5) |
Diabetes | 86 (12) |
Smoking | 59 (8) |
Normally distributed continuous variables are presented as means ± standard deviations, skewed continuous variables as medians (interquartile ranges; IQR25–IQR75), and categorical variables as n (%). HDL, high-density lipoprotein.
Glomerular filtration rate was estimated from serum cystatin C (mL/min/1.73 m2).
Creatinine-adjusted osteopontin.