Table 2.
Summary of test results. The improvement and worsening of lesion-induced parkinsonian symptoms by DBS are marked by (+) and (−), respectively. Borderline changes (0.05 < p ≤ 0.08) are marked by (b); parameters with no detectable DBS effects are marked (0); n.d. stands for “not determined.” The results marked with an asterisk could not be interpreted in terms of the therapeutic DBS effects.
| Group name | Rotation test | Stepping test initiation time |
Stepping test contralateral bias | Corridor test | Open-field test | ||
|---|---|---|---|---|---|---|---|
| Contralateral paw | Forehand | Backhand | Total distance | Distance ratio∗ | |||
| 6-OHDA_bi_3 d | b+ | + | 0 | 0 | 0 | — | Up |
| 6-OHDA_bi_3 w | b+ | b+ | 0 | 0 | 0 | — | 0 |
| 6-OHDA_uni_ 3 d | + | b− | 0 | 0 | 0 | — | 0 |
| 6-OHDA_uni_ 3 w | + | 0 | 0 | 0 | + | 0 | Up |
| 6-OHDA_uni_ 3 w + 3 d off | 0 | 0 | 0 | 0 | n.d. | + | Up |
| 6-OHDA_uni_ 6 w | 0 | b+ | — | 0 | 0 | b− | Up |
| 6-OHDA_uni_ 3 w + 3 w off | 0 | + | 0 | 0 | b+ | 0 | 0 |