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. 2017 Jun 6;292(28):11970–11979. doi: 10.1074/jbc.M116.771089

Figure 8.

Figure 8.

Schematic diagram of the effect of NE on CSE-induced HO-1 expression. CSE up-regulates HO-1 through Nrf2 activation as a defense mechanism in human bronchial epithelial cells. NE suppresses CSE-induced HO-1 by cleaving SIRT1 protein.