Table 2.

Echocardiographic and morphometric characterization 2 weeks and 6 weeks after surgery.

		Sham		MI
		WT	S100A4 KO	WT	S100A4KO
		n = 4	n = 4	n = 13	n = 12
2 week after	LVEDV,µl	71.44 ± 26.75	64.77 ± 2.73	109.5 ± 7.96	97.18 ± 24.59
	EF, %	41.67 ± 2.180	41.39 ± 2.69	29.07 ± 2.92*	21.70 ± 1.519#
	HR, bpm	424 ±12	448 ± 14	471 ± 14	440 ± 23
		WT	S100A4KO	WT	S100A4KO
		n = 10	n = 10	n = 13	n = 12
6 weeks after	LVEDV, µl	73.99 ± 4.967	66.56 ± 8.83	90.46 ± 7.94	116.3 ± 11.26#
	EF,%	45.05 ± 3.990	42.22 ± 7.54	23.28 ± 2.56*	14.56 ± 2.16#
	+ dP/dt	9108 ± 1693	10,026 ± 1298	5661 ± 359.4*	4513 ± 291#
	− dP/dt	7678 ± 291	7249 ± 581	4951 ± 292*	3607 ± 238#
	HW/BW mg/g	4.71 + ±0.3	4.2 ± 0.34	5.3 + ±0.2*	5.2 ± 0.19*

Characterization of mice after Sham or MI by morphometry and echocardiography.

Abbreviations: n: number of mice analyzed; LVEDV, µl: left ventricular end diastolic volume; EF, %: ejection fraction. HR, bpm: Heart rate; dP/dt: first derivative of left ventricular pressure. BW, body weight; HW: heart weight; HW/BW: heart weight/body weight ratio.

^*p < 0.05 vs Sham.

^#p < 0.05 vs WT MI.