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(A) Structures of the double- or triple-substituted peptides. The numbers above each amino acid indicate its position in the prodomain sequence of mouse myostatin. (B) The luciferase reporter assay determined the activities of the double- and triple-substituted peptides toward myostatin inhibition relative to peptide 1. Peptide concentration: 1 μM. Results are presented as mean values ± SD (n = 3).
