Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model depicting functional selectivity of GPCR signaling. A balanced agonist would be predicted to activate multiple signaling cascades mediated by the effectors that associate with the receptor, while a biased agonist would preferentially engage with certain effectors over others to activate distinct signaling pathways.
