Fig. 7.

BaP activates sphingolipid, FFA and phospholipid metabolism in alveolar type II cells. (A-G) Levels of Cer (A), GlcCer, LacCer, C1P (B), SM (C), DHSM, DHCer, DHGlcCer, DHC1P (D), Sulfatide (E), S1P, So, Sa (F), and FFA (G) in A549 cells. (H, I) Ratios for PUFA/FFA (H) and ω–3/ω–6 PUFA (I) in A549 cells. (J, K) Levels of LPC (J), and PC (K) in A549 cells. (L) Ratio for LPC/PC in A549 cells. A549 cells were treated with control or BaP (4 μM) for 6 h (n = 5–6). All of the data are presented as the means ± SEM. Two-tailed Student's t-test: * P < 0.05, ** P < 0.01 compared with the control group.