TABLE 1.

List of ApoE variants used in this study

Isoform	Amino acid at position (1–299):				Charge relative to ApoE3	Variant to which the isoform corresponds (dsSNPa identifier)
	112	139	146	158
ApoE1	Cys	Ser	Glu	Arg	−2	rs121918394
ApoE2	Cys	Ser	Lys	Cys	−1	rs7412
ApoE3b	Cys	Ser	Lys	Arg	0
ApoE4	Arg	Ser	Lys	Arg	+1	rs429358
ApoE4Ac	Cys	Arg	Lys	Arg	+1

^adbSNP URL: https://www.ncbi.nlm.nih.gov/SNP/.

^bRepresents the prototype ApoE (UniProt accession number P02649 and GenBank accession number K00396).

^cRepresents an artificial ApoE mutant.