TABLE 1.
VP4 protein sequence comparison for different rotavirus strains
| Rotavirus strain | Amino acid at VP4 protein positiona: |
Induction of murine BAb | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 440 | 441 | 442 | 443 | 444 | 445 | 446 | 447 | 448 | ||
| RRV | T | R | T | R | V | S | R | L | Y | Yes |
| TUCH | V | R | T | R | I | S | G | L | Y | No |
| Ro1845 | M | R | T | R | V | S | G | L | Y | No |
| SA-11 | T | R | T | R | L | D | R | L | Y | Yes |
| NCDV | L | R | T | R | V | S | G | L | Y | No |
| Wa | L | R | T | R | T | V | N | L | Y | No |
| EDIM | T | R | T | R | V | S | G | L | Y | No |
| CU-1 | M | R | T | R | V | S | G | L | Y | No |
| WC-3 | T | R | T | R | V | S | K | L | Y | No |
| VA-70 | M | R | T | R | I | V | N | L | Y | No |
| EB | T | R | T | R | V | S | G | L | Y | No |
| EMcN | T | R | T | R | V | S | G | L | Y | No |
| ST-3 | T | R | T | R | V | S | K | L | Y | No |
| GRV | T | R | T | R | V | S | R | L | Y | Yes |
| KU | L | R | T | R | T | V | N | L | Y | No |
a
According to analysis of rotavirus VP4 amino acid sequences obtained from the NCBI database. The arginine residue at position 446 is indicated in bold.
b
Bile duct obstruction was determined by histology.