FIG. 1.

Cultured OPCs proliferate and differentiate into oligodendrocyte in three-dimensional (3D) gels: (a) representative image for PDGF-Rα staining of cells on day 1 (left) and day 3 (right). Scale bar: 100 μm. (b) Cell numbers for PDGF-Rα-positive cells on day 1 and day 3. *P < 0.01 of N = 5, mean ± SD. (c, d) mRNA levels of PDGF-Rα (c) and MBP (d) on day 3 and 10. *P < 0.01 of N = 4, mean ± SD. Please see Supplementary Fig. S1 and Supplementary Video S1 for 3D images of our OPC culture. OPC, oligodendrocyte precursor cell; PDGF-Rα, platelet-derived growth factor receptor α; SD, standard deviation. Color images available online at www.liebertpub.com/scd