Table 2.

The Sequential Organ Failure Assessment (SOFA) score

SOFA score	1	2	3	4
Respiration			-----with respiratory support-----
PaO2/FiO2 (mm Hg)	<400	<300	<200	<100
Coagulation
Platelets ×103/mm3	<150	<100	<50	<20
Liver
Bilirubin (mg dL−1)	1.2–1.9	2.0–5.9	6.0–11.9	>12.0
Cardiovascular
Hypotension	MAP <70	Dopamine ≤5 or dobutamine (any)	Dopamine >5 or norepinephrine ≤0.1	Dopamine >15 or norepinephrine >0.1
Central Nervous System
Glasgow Coma Score	13–14	10–12	6–9	<6
Renal
Creatinine (mg dL−1) or urine output (mL)	1.2–1.9	2.0–3.4	3.5–4.9 or <500	>5.0 or <200

MAP: mean arterial pressure; vasoactive mediations administered for at least 1 hr (dopamine and norepinephrine μg kg⁻¹ min⁻¹).