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The multifunctional envelope-type nano device (MEND) has a condensed nucleotide core coated with lipid envelope. The lipid envelope contains membrane fusogenic lipids and is further modified with PEG, targeting ligand and protein transduction domain peptides. Reproduced width permission from [58], K. Kogure et al., Multifunctional envelope-type nano device (MEND) as a non-viral gene delivery system. Adv. Drug Deliv. Rev. 60, 559 (2008). © 2006.
