Table 3.
Outcome | Events N (%) |
Crude | Model 1* | Model 2† | |||
---|---|---|---|---|---|---|---|
HR (95% CI) |
P-value | HR (95% CI) |
P-value | HR (95% CI) |
P-value | ||
Heart failure hospitalization‡ | |||||||
• No pulmonary hypertension | 24 (10) | 1.0 (ref) | — | 1.0 (ref) | — | 1.0 (ref) | — |
• Pulmonary hypertension present | 16 (27) | 3.19 (1.70, 6.02) | <0.001 | 2.90 (1.45, 5.81) | 0.003 | 2.37 (1.15, 4.86) | 0.0189 |
Death | |||||||
• No pulmonary hypertension | 70 (22) | 1.0 (ref) | — | 1.0 (ref) | — | 1.0 (ref) | — |
• Pulmonary hypertension present | 39 (44) | 2.39 (1.62, 3.54) | <0.001 | 1.83 (1.21, 2.76) | 0.004 | 1.37 (0.89, 2.13) | 0.16 |
Model 1 adjusted for age, sex, diabetes mellitus, estimated glomerular filtration rate, and ejection fraction.
Model 2 adjusted for b-type natriuretic peptide in addition to covariates in model 1.
Because of missing data on heart failure hospitalization (N=106), the total N for this analysis is 302 (242 in the no PH group and 60 in the PH group). Please see method sections for more details.
HR, hazard ratio; CI, confidence interval.