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. 2017 Jul;23(7):1155–1159. doi: 10.3201/eid2307.151251

Table 2. Disease characteristics, demographics, clinical characteristics, therapy, and outcomes of 7 solid organ transplant recipients with VL, Madrid, Spain, January 1, 2005–January 1, 2013*.

Characteristics Patient no.
1 2 3 4 5 6 7
Sex M M M M M F M
Race Black Black White White White White White
Linear distance from patient’s residence to park, m 794 399 261 1,240 985 233 358
Age at transplant, y 35 34 76 55 68 49 52
Type of SOT Kidney Kidney Kidney Kidney Kidney Heart Kidney
Donor Leishmania spp. serostatus Negative NP Negative NP Negative Negative Negative
Pretransplant recipient Leishmania spp. serostatus NP NP Negative Positive Negative Negative Negative
Date of transplant 2011 Feb 11 2010 Jan 22 2010 Mar 10 2010 Jul 7 2009 Dec 29 2010 Sep 5 2010 Apr 15
Interval from transplant to VL diagnosis, y 1.17 2.44 0.25 1.4 0.17 1.81 2.21
Fever at admission Yes Yes No Yes Yes Yes Yes
Pancytopenia Yes Yes Yes Yes Yes Yes Yes
Splenomegaly Yes Yes Yes Yes Yes Yes Yes
Serologic testing results for Leishmania spp. Positive Negative Negative Positive Negative Positive Negative
Presence of amastigote forms in bone marrow sample Positive Positive Positive Positive Positive Positive Positive
PCR assay results of bone marrow sample NP NP NP Negative NP NP NP
NNN culture results of bone marrow sample Positive NP Positive Negative Negative Positive Negative
Initial therapy L-AmB L-AmB L-AmB L-AmB L-AmB L-AmB L-AmB
Relapse Yes No Yes Yes No No No
Outcome Renal failure Graft loss Cured Graft loss Cured Cured Cured

*L-AmB, liposomal amphotericin B; NNN, Novy-McNeal-Nicolle; NP, not performed; SOT, solid organ transplant; VL, visceral leishmaniasis.