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. 2017 Jun 5;8:15564. doi: 10.1038/ncomms15564

Figure 5. POP2 improves resistance to bacterial infections.

Figure 5

(a–c) Per cent survival and mean body weight loss±s.d. in (a) POP2 (n=12) and LMC (n=14) mice after subcutanesous infection with 1.5 × 105 c.f.u. of F. novicida, (b) POP2 (n=10) and LMC (n=10) mice after intranasal (i.n.) infection with 500 c.f.u. (LD50) of F. tularensis (left panel) and in POP2 (n=12) and LMC (n=12) mice after i.n. infection with 1,000 c.f.u. (lethal) of F. tularensis (right panel) and (c) POP2 (n=12) and LMC (n=12) mice after i.n. infection with 1 × 105 c.f.u. of S. pneumoniae. Data represent per cent of surviving mice and accompanying weight loss from at least two independent experiments. To determine significance for survival data, the Log-rank test was used, and for weight data, Student’s t-test was used. P values are shown where significance was detected.