REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Anti-mouse CD3e Biotin	TONBO	30-0031
Anti-mouse CD4 Biotin	Biolegend	100404
Anti-mouse CD8 Biotin	Biolegend	100704
Anti-mouse CD19 Biotin	TONBO	30-0193
Anti-mouse B220 Biotin	TONBO	30-0452
Anti-mouse CD11b Biotin	TONBO	30-0112
Anti-mouse Gr1 Biotin	TONBO	30-5931
Anti-mouse CD11c Biotin	TONBO	30-0114
Anti-mouse Ter119 Biotin	TONBO	30-5921
Anti-mouse CD49b Biotin	eBioscience	13-5971
Anti-mouse ICOS	Biolegend	117405
Anti-mouse CD90.2	BD	553007
Anti-mouse CD25	BD	557658
Anti-mouse Sca1	BD	560653
Anti-mouse CD45.2	TONBO	80-0454
Anti-mouse ST2	eBioscience	46-9335
Anti-mouse CD127	TONBO	60-1271
Anti-mouse Ki67	Biolegend	652403
Anti-mouse IL-4	BD	564004
Anti-mouse IL-5	BD	562048
Anti-mouse IL-13	eBioscience	25-7133
Anti-mouse Gata3	eBioscience	50-9966
Anti-mouse CXCR6	R & D	FAB2145P
Anti-mouse LPAM-1	BD	562376
Anti-mouse PLZF	Sant Cruz Biotechnology	Sc-28319
Anti-mouse CD117	Biolegend	105824
Anti-mouse Rorgt	eBioscience	12-6988
Anti-mouse CD117	eBioscience	47-1172
Anti-mouse CCR6	Biolegend	129818
Anti-mouse CD335	BD	560800
Anti-mouse Ly6D	Biolegend	138603
Anti-mouse Flt3	eBioscience	17-1351
Anti-mouse CD150	Biolegend	115925
Anti-mouse Sca1	BD	561229
Anti-mouse B220	TONBO	65-0452
Anti-mouse CD19	BD	552854
Anti-mouse CD4	Biolegend	100528
Anti-mouse CD8	BD	553033
Anti-mouse CD25	Biolegend	102033
Anti-mouse CD44	BD	559250
Streptavidin BV650	BD	563855
Bacterial and Virus Strains
Biological Samples
Chemicals, Peptides, and Recombinant Proteins
Recombinant Murine SCF	PeproTech	250-03
Recombinant Murine IL-7	PeproTech	217-17
Recombinant Murine flt3-Ligand	PeproTech	250-31L
Critical Commercial Assays
Lung Dissociation Kit	Miltenyi Biotec	130-095-927
BD BrdU flow kit	BD Biosciences	552598
Foxp3/Transcription Factor Staining Buffer Kit	TONBO	TNB-0607-KIT
Intracellular Fixation & Permeabilization Buffer Set	eBioscience	88-8824-00
RNeasy-Micro Kit	Qiagen	74004
SMARTer Ultra Low Input RNA kit for Sequencing-v3	Clontech	CLN 634848
Low Input Library Prep Kit	Clontech	CLN634947
Deposited Data
RNA-seq and ATAC-seq	This paper	GEO:GSE95339
ATAC-seq	Shih et al., 2016	GEO:GSE77695
Experimental Models: Cell Lines
Mouse: Tst-4-DL1 stroma cells	Miyazaki et al., 2005	N/A
Experimental Models: Organisms/Strains
Mouse: C57BL/6J	Japan SLC, Inc.	C57BL/6JJmsSlc
Mouse: Tcf3fl/fl	Jones and Zhuang, 2007	N/A
Mouse: Tcf12fl/fl	Jones and Zhuang, 2007	N/A
Mouse: Id2/+TA/+	This paper	N/A
Mouse: Tcf3E2A-gfp/E2A-gfp	Zhuang et al., 2004	N/A
Mouse: E47−/−	Engel et al., 2001	N/A
Mouse: Id2yfp/+	Yang et al., 2011	N/A
Mouse: Id2fl/fl	Niola et al., 2012,	N/A
Mouse: Il7rCre	Schlenner et al., 2010	N/A
Mouse: Zbtb16GFPcre+/−	The Jackson Laboratory	JAX: 024529
Mouse: ERT2cre	The Jackson Laboratory	JAX: 008463
Mouse: ROSAYFP/YFP	The Jackson Laboratory	JAX: 006148
Oligonucleotides
Recombinant DNA
Software and Algorithms
FlowJo software	Tree Star, Inc.	N/A
Bowtie	Langmead et al., 2009	http://bowtie-bio.sourceforge.net/index.shtml
TopHat	Trapnell et al., 2009	https://ccb.jhu.edu/software/tophat/index.shtml
HOMER	Heinz et al., 2010	http://homer.salk.edu
Metascape		http://metascape.org/
GraphPad Prism 6	GraphPad Software	N/A
Other