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. 2017 Jul 14;16:119. doi: 10.1186/s12943-017-0689-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Hif-2α was associated with poor prognosis in patients with pancreatic cancer. a-c In pancreatic cancer tissue array, overexpression of hif-2α was correlated with abundant stroma, high microvascular density within tumors as well as short tumor-vessel distance. d Patients with high expression of hif-2α had significantly shorter survival compared to those with low hif-2α expression. e Representatives of successive series of PDAC tissue showed overexpression of vimentin in tumors with high hif-2α expression