Table 1.

Comparison of high throughput sequencing (HTS) systems available from the manufacturers Ion Torrent, Illumina Platform, and Pacific Biosciences.

	Ion Torrent		Illumina Platform
	Personal Genome Machine	Ion Proton	MiSeq	HiSeq	NextSeq	Pacific Biosciences
Read length	400 bp	75 bp	250 bp	250 bp	150 bp	>15 Kb
Depth of Reads	10 million	80 million	15 million	1 Billion	500 Million	50,000
Other considerations	High error rates in regions of homopolymers		Short-read length make mapping repetitive or highly similar regions very difficult			Long reads that can sequence across tandemly duplicated regions.