Table 2.
Clinical and dietary data; comparing ASCA IgG ≥ 10 U/mL to IgG < 10 U/mL a
| IgG ≥ 10 U/mL | n | IgG < 10 U/mL | n | Adjusted for age, gender and BMI b | P-value | |
|---|---|---|---|---|---|---|
| Odds Ratio (95% CI) | ||||||
| Age, years | 45.3 (7.9) | 31 | 42.5 (8.8) | 109 | 1.06 (1.00–1.11) | 0.04 * |
| Gender (male/female) | 9 (29%)/22 (71%) | 31 | 22 (20%)/87 (80%) | 109 | 1.29 (0.49–3.36) | 0.61 |
| Height, cm | 172 (161–197) | 31 | 168 (149–192) | 109 | 1.09 (1.01–1.16) | 0.02 c, * |
| Weight, kg | 128 (95–183) | 31 | 118 (90–192) | 109 | 1.04 (1.01–1.07) | <0.01 c, * |
| BMI, kg/m2 | 42.8 (3.9) | 31 | 41.9 (3.8) | 109 | 1.10 (0.98–1.24) | 0.10 |
| Body fat, percentage of body weight | 48 (33–50) | 31 | 47 (31–51) | 109 | 1.22 (0.94–1.58) | 0.14 c |
| Body fat mass, kg | 59 (43–75) | 31 | 53 (39–81) | 109 | 1.07 (1.02–1.13) | 0.01 c, * |
| Dietary intake | ||||||
| Bread, g | 148 (24–267) | 23 | 174 (48–444) | 75 | 1.00 (0.99–1.00) | 0.39 |
| Beer, g | 0 (0–180) | 23 | 0 (0–140) | 75 | 1.01 (0.99–1.02) | 0.35 |
| Bread, buns and other baked goods + beer, g | 172 (24–387) | 23 | 187 (53–1060) | 75 | 1.00 (0.99–1.00) | 0.39 |
| Energy, kJ | 9293 (5100–20,111) | 23 | 9737 (4830–21,816) | 75 | 1.00 (1.00–1.00) | 0.58 |
| Carbohydrates, g | 251 (79–475) | 23 | 247 (94–903) | 75 | 1.00 (0.99–1.00) | 0.60 |
| Proteins, g | 109 (64–177) | 23 | 108 (43–213) | 75 | 1.00 (0.99–1.02) | 0.99 |
| Fats, g | 82 (27–231) | 23 | 93 (38–283) | 75 | 1.00 (0.99–1.01) | 0.61 |
| Alcohol, g | 0.6 (0–10) | 23 | 1.3 (0–21) | 75 | 0.93 (0.79–1.08) | 0.33 |
| Physical activity (light) d | 31 | 109 | ||||
| < 1 h/week (reference) | 7 (23%) | 30 (28%) | ||||
| 1–2 h/week | 13 (42%) | 43 (39%) | 1.54 (0.53–4.54) | 0.43 | ||
| ≥ 3 h/week | 11 (35%) | 36 (33%) | 1.69 (0.55–5.22) | 0.36 | ||
| Physical activity (strenuous) d | 31 | 109 | ||||
| < 1 h/week (reference) | 17 (55%) | 66 (61%) | ||||
| ≥ 1 h/week | 14 (45%) | 43 (39%) | 1.23 (0.54–2.80) | 0.62 | ||
| Smoking | 31 | 109 | ||||
| Never (reference) | 13 (42%) | 42 (39%) | ||||
| Former | 14 (45%) | 46 (42%) | 0.90 (0.36–2.24) | 0.83 | ||
| Current | 4 (13%) | 21 (19%) | 0.78 (0.21–2.83) | 0.70 | ||
| Previous or present co-morbidity | ||||||
| Hypertension | 10 (32%) | 31 | 36 (33%) | 109 | 0.65 (0.25–1.70) | 0.38 |
| Diabetes mellitus | 9 (29%) | 31 | 17 (16%) | 109 | 1.98 (0.74–5.32) | 0.18 |
| Hypothyroidism | 6 (19%) | 31 | 12 (11%) | 109 | 1.89 (0.62–5.74) | 0.26 |
| Irritable Bowel Syndrome | 8 (27%) | 30 | 27 (26%) | 105 | 1.25 (0.47–3.28) | 0.66 |
| Mental distress (HSCL-10 score > 1.85) | 12 (39%) | 31 | 22 (20%) | 109 | 2.53 (1.04–6.17) | 0.04 * |
aData are expressed as mean (SD), median (min-max) and n (%)
bBased on logistic regression with ASCA IgG dichotomized at cut-off 10 as the dependent variable and age, gender, BMI and one by one of the column variables as independent variables
cAdjusted for age and gender only
dCategories are collapsed as compared to originally four categories; no significant differences between the groups were seen when all original categories were included (data not shown)
*Statistically significant P < 0.05